Ella is most effective if taken right away, but it can be used for up to 120 hours (5 days) after unprotected sex.

Other emergency contraception options, Plan B One-Step, Next Choice One Dose, My Way, Take Action, and Next Choice, are FDA-approved to be used up to 72 hours (three days) after contraceptive failure or unprotected intercourse.

Usage

Ella is thought to work for emergency contraception primarily by stopping or delaying the release of an egg from the ovary, so no egg will be available for a sperm to fertilize.

Though Ella prevents ovulation for as long as five days after unprotected sex, there is some concern that women may mistakenly believe that once taking Ella, it can further protect them against pregnancy from any additional acts of unprotected sex for five days. This is not the case, as sperm from additional sex can outlive the initial five-day window.

Ella belongs to a class of drugs called selective progesterone receptor modulators. The only other approved drug in this class is mifepristone, better known as RU-486. Mifepristone is approved for use as part of a regimen that induces abortion.

Because it is better absorbed by the body than mifepristone, Ella can be used at low doses that prevent conception but that should not cause abortion. It remains unclear, though, whether Ella might increase the rate of spontaneous abortion in the few women who become pregnant despite using the drug.

There is also confusion as to whether or not Ella may cause harm to an existing pregnancy (if the woman is actually pregnant when taking Ella), although there is currently no substantial evidence that it does.

What It Is Not

Emergency contraception is often mistakenly confused with the early abortion pill, RU486 (also referred to as M&M, Mifeprex, mifepristone or medical abortion). These two medications serve two different purposes and work completely differently from one another.

According to the FDA, Ella is not for use to end an existing pregnancy.

When to Use

To reduce the risk of an unplanned pregnancy, Ella should be taken as soon as possible within 120 hours (five days) of unprotected sex or contraceptive failure. The sooner Ella is taken, the more effective it’ll be.

Ella can also be used any time during your menstrual cycle and can be taken with or without food.

Who Should Not Use It

Ella is not intended to be used as a substitute for routine contraception use—it does not work as well as most other forms of birth control when they are used consistently and correctly.

Do not take Ella if you know or suspect you are already pregnant. If there is a chance you could already be pregnant, your healthcare provider should provide you with a pregnancy test before prescribing Ella. The risks to a fetus when Ella is administered to a pregnant woman are unknown.

Side Effects

When used as directed, Ella is safe for most women. The most common side effects reported during clinical trials of 2,637 women receiving Ella included:

Headache (18%)Nausea (12%)Abdominal and upper abdominal pain (12%)Dysmenorrhea (uterine pain during menstruation) (10%)Fatigue (6%)Dizziness (5%)

After taking Ella, you could likely experience changes in your period. In some cases, your next period may be heavier or lighter, or earlier or later.

If you are experiencing severe abdominal pain three to five weeks after taking Ella, there could be the possibility that you’re having an ectopic pregnancy, so you should seek immediate medical attention.

Effectiveness

Ella is most effective the sooner it is started. When taken as directed (within 120 hours of unprotected sex or contraceptive failure), Ella will reduce the chance that you will get pregnant.

Ella is not effective in every case and is only to be used for a single episode of unprotected intercourse. During clinical trials, Ella significantly reduced the pregnancy rate from an expected rate of 5.5% (the number of pregnancies expected without emergency contraception calculated based on the timing of intercourse with regard to each woman’s menstrual cycle) to an observed rate of 2.2%.

Ella appears to be less effective in obese women. During clinical trials, obese women were twice as likely to become pregnant compared with non-obese women.

A rapid return to fertility is expected following treatment with Ella for emergency contraception. Therefore, some form of birth control should be used following its use to ensure the prevention of pregnancy. 

Certain medications and herbal products could also decrease the effectiveness of Ella. These include:

BarbituratesBosentanCarbamazepineFelbamateGriseofulvinOxcarbazepinePhenytoinRifampinSt. John’s WortTopiramate

Precautions

Talk to your healthcare provider if you use hormonal birth control (like the pill, the patch, Depo Provera, NuvaRing).

Depending on your healthcare provider, you may or may not need an office visit in order to receive an Ella prescription. The manufacturer advises medical providers to confirm or rule out an existing pregnancy before writing a prescription for Ella.

As a precaution, you can ask your healthcare provider about obtaining a prescription for Ella to have ahead of time—just in case an emergency occurs. This way, you will already have a prescription to be filled immediately and will not need to wait to get a medical appointment.

Costs

Prices for this morning-after pill vary depending on where you purchase it. Ella may cost at least $55 at the pharmacy. There is an online prescription service that you can use to purchase Ella for $67, plus free shipping and handling for next-day delivery. 

STI Protection

Ella offers no protection against sexually transmitted infections or HIV.